Patient Reported Outcome Measures of Pharmaceutical Therapyfor Quality of Life (PROPMPT-QOL) among Saudi Population: A Real World Observational Study
Main Article Content
Keywords
PROMPT-QOL questionnaire, patient education, pharmaceutical therapy, foster therapeutic relationships, quality of life
Abstract
Introduction: Patient-reported outcomes in pharmaceutical therapy play a crucial role in understanding medication experiences and their impact on quality of life among chronic disease patients. This study aims to explore patient-reported outcomes in pharmaceutical therapy among chronic disease patients in Saudi Arabia, with a focus on medication experiences and their impact on quality of life. Methods: The study utilized a cross-sectional design, collecting self-reported data from participants recruited primarily from healthcare settings. Participants completed the PROMPT-QOL questionnaire, which assessed various domains related to medication use and quality of life. Results: The findings revealed positive attitudes towards medication use and perceived effectiveness among participants. However, they also reported experiencing various side effects and impacts, particularly in intimate aspects of life such as sexual desire or relationships, vision, hearing, speech, and social activities. Notably, participants placed significant value on clear and comprehensive medication information, indicating the importance of patient education in promoting adherence and satisfaction. Conclusion: The study underscores the critical role of effective information provision and holistic patient care in optimizing pharmaceutical therapy outcomes. Healthcare providers should prioritize patient education, foster therapeutic relationships, and involve patients in shared decision-making to enhance treatment outcomes and overall quality of life for chronic disease patients. Additionally, longitudinal and comparative studies are needed to further explore medication experiences and healthcare disparities across different populations and settings.
References
Pharmacy Vol 2001, 18.
2. Krijnen, P.; Van Jaarsveld, B.; Hunink, M.; Habbema, J. The effect of treatment on health-related quality of life in patients with
hypertension and renal artery stenosis. Journal of human hypertension 2005, 19, 467-470.
3. Krähenbühl-Melcher, A.; Schlienger, R.; Lampert, M.; Haschke, M.; Drewe, J.; Krähenbühl, S. Drug-related problems in hospitals: a review of the recent literature. Drug safety 2007, 30, 379-407.
4. Hanlon, J.T.; Lindblad, C.I.; Gray, S.L. Can clinical pharmacy services have a positive impact on drug-related problems and health outcomes in community-based older adults? The American journal of geriatric pharmacotherapy 2004, 2, 3-13.
5. Sakthong, P.; Suksanga, P.; Sakulbumrungsil, R.; Winit-Watjana, W. Development of Patient-reported Outcomes Measure of
Pharmaceutical Therapy for Quality of Life (PROMPT-QoL): A novel instrument for medication management. Research in Social
and Administrative Pharmacy 2015, 11, 315-338.
6. de Freitas, G.R.M.; Tramontina, M.Y.; Balbinotto, G.; Hughes, D.A.; Heineck, I. Economic impact of emergency visits due to
drug-related morbidity on a Brazilian hospital. Value in Health Regional Issues 2017, 14, 1-8.
7. Neame, R.; Hammond, A. Beliefs about medications: a questionnaire survey of people with rheumatoid arthritis. Rheumatology 2005, 44, 762-767.
8. Hanlon, J.T.; Shimp, L.A.; Semla, T.P. Recent advances in geriatrics: drug-related problems in the elderly. Annals of
Pharmacotherapy 2000, 34, 360-365. 9. Silva, L.D.; da Cunha, C.C.; da Cunha, L.R.; Araújo, R.F.; Barcelos, V.M.; Menta, P.L.; Neves, F.S.; Teixeira, R.; Rocha, G.A.; Gontijo, E.D. Depression rather than liver impairment reduces quality of life in patients with hepatitis C. Revista Brasileira de Psiquiatria 2015, 37, 21-30.
10. Ponticelli, C.; Sala, G.; Glassock, R.J. Drug management in the elderly adult with chronic kidney disease: a review for the
primary care physician. In Proceedings of the Mayo Clinic Proceedings, 2015; pp. 633-645.
11. Krska, J.; Morecroft, C.W.; Poole, H.; Rowe, P.H. Issues potentially affecting quality of life arising from long-term medicines use: a qualitative study. International journal of clinical pharmacy 2013, 35, 1161-1169.
12. Heydari, A.; Ziaee, E.S.; Gazrani, A. Relationship between awareness of disease and adherence to therapeutic regimen among cardiac patients. International journal of community based nursing and midwifery 2015, 3, 23.
13. Epstein, R.M.; Street, R.L. The values and value of patient-centered care. Annals Family Med 2011, 9, 100-103.
14. Chow, A.; Mayer, E.K.; Darzi, A.W.; Athanasiou, T. Patient-reported outcome measures: the importance of patient satisfaction in surgery. Surgery 2009, 146, 435-443.
15. Saarni, S.I.; Härkänen, T.; Sintonen, H.; Suvisaari, J.; Koskinen, S.; Aromaa, A.; Lönnqvist, J. The impact of 29 chronic conditions on health-related quality of life: a general population survey in Finland using 15D and EQ-5D. Quality of Life Research 2006,
15, 1403-1414.
16. Rothman, M.L.; Beltran, P.; Cappelleri, J.C.; Lipscomb, J.; Teschendorf, B.; Group, M.F.P.-R.O.C.M. Patient-reported outcomes:
conceptual issues. Value in Health 2007, 10, S66-S75.
17. Berlim, M.T.; Fleck, M. “ Quality of life”: a brand new concept for research and practice in psychiatry. Revista Brasileira de
Psiquiatria 2003, 25, 249-252.
18. Sakthong, P.; Sakulbumrungsil, R.; Winit-Watjana, W. Medication-therapy-related quality of life measurement using the
patient-generated index: a pilot study. Int J Pharm Pharm Sci 2013, 5, 153-156.
19. Kheir, N.M.; van Mil, J.F.; Shaw, J.P.; Sheridan, J.L. Health-related quality of life measurement in pharmaceutical care Targeting an outcome that matters. Pharmacy World and Science 2004, 26, 125-128.
20. Arun, K.; Murugan, R.; Kanna, M.; Rajalakshmi, S.; Kalaiselvi, R.; Komathi, V. The impact of pharmaceutical care on the clinical outcome of diabetes mellitus among a rural patient population. International journal of diabetes in developing countries 2008, 28, 15.
21. Young, Y.; Alharthy, A.; Hosler, A.S. Transformation of Saudi Arabia’s health system and its impact on population health: what can the USA learn? Saudi Journal of Health Systems Research 2021, 1, 93-102.
22. Björndell, C.; Premberg, Å. Physicians’ experiences of video consultation with patients at a public virtual primary care clinic: a qualitative interview study. Scandinavian Journal of Primary Health Care 2021, 39, 67-76.
23. Yaacoub, J.-P.A.; Noura, M.; Noura, H.N.; Salman, O.; Yaacoub, E.; Couturier, R.; Chehab, A. Securing internet of medical things systems: Limitations, issues and recommendations. Future Generation Computer Systems 2020, 105, 581-606.
24. Baker, L.; Wagner, T.H.; Singer, S.; Bundorf, M.K. Use of the Internet and e-mail for health care information: results from a
national survey. Jama 2003, 289, 2400-2406.
25. Sakthong, P.; Sonsa-Ardjit, N.; Sukarnjanaset, P.; Munpan, W. Psychometric properties of the EQ-5D-5L in Thai patients with
chronic diseases. Quality of Life Research 2015, 24, 3015-3022.
26. Sakthong, P. Pharmacotherapy related quality of life in Thai patients with chronic diseases. International Journal of Clinical
Pharmacy 2019, 41, 1004-1011.
27. DiMatteo, M.R.; Giordani, P.J.; Lepper, H.S.; Croghan, T.W. Patient adherence and medical treatment outcomes: a metaanalysis. Medical care 2002, 40, 794-811.
28. McDonald, H.P.; Garg, A.X.; Haynes, R.B. Interventions to enhance patient adherence to medication prescriptions: scientific
review. Jama 2002, 288, 2868-2879.
29. Ingersoll, K.S.; Cohen, J. The impact of medication regimen factors on adherence to chronic treatment: a review of literature. Journal of behavioral medicine 2008, 31, 213-224.
30. Unni, E.J.; Sternbach, N.; Goren, A. Using the Medication Adherence Reasons Scale (MAR-Scale) to identify the reasons for non-adherence across multiple disease conditions. Patient preference and adherence 2019, 993-1004.
31. Mukhtar, O.; Weinman, J.; Jackson, S.H. Intentional non-adherence to medications by older adults. Drugs & aging 2014, 31,
149-157.