Associated factors and evaluation of interventional medication errors among inpatients in a hospital setting in Vietnam
Main Article Content
Keywords
Medication errors (MEs), Inpatients, Interventions, Prescription, Transcription
Abstract
This study aimed to determine factors associated with medication errors, and evaluate the results of interventions to reduce medication errors in inpatients treatment at Hoan My Minh Hai General Hospital, Vietnam. Methods: A single-blind, before-and-after and interventional study was conducted on 442 medical records of inpatients in the pre-intervention stage and 442 medical records of inpatients in the post-intervention stage at the Department of Pediatrics, Department of General Internal Medicine, Department of Cardiology - Endocrinology, Department of Surgery, Department of Obstetrics of Hoan My Minh Hai General Hospital from July 1, 2021, to March 31, 2022. Data were collected and processed using Excel 2016 and SPSS 26.0 software. Results: The medication errors rate decreased from 7.70% in the pre-intervention stage to 5.70% in the post-intervention stage, the difference was statistically significant (p<0.001). Medication errors before intervention occurred most often in the preparation and implementation stage (2.04%), after the intervention, the rate decreased to 1.81%. The replication stage had a high rate of medication errors (2.04%), after the intervention it decreased to 1.81%. The most common medication errors before intervention were wrong doses and wrong drugs (1.58%), after intervention, wrong dose errors rate decreased to 1.36%, the rate of wrong drug errors rate decreased to 1.13%. The total number of diseases ≥2 was significantly related to the occurrence of medication errors (p<0.05). Conclusion: Medication errors could occur at different stages of medication use processes. Pharmacist interventions appear to decrease the incidence of medication errors
References
2. FDA. Working to Reduce Medication Errors. 2019. Available from URL: https://www.fda.gov/drugs/information-consumers-and-patients-drugs/working-reduce-medication-errors.
3. Rodziewicz TL, Houseman B. Medical error reduction and prevention. StatPearls. 2022.
4. Manias E, Kusljic S, Wu A. Interventions to reduce medication errors in adult medical and surgical settings: a systematic review. Therapeutic Advances in Drug Safety. 2020;11:204209862096830. https://doi.org/10.1177/2042098620968309
5. Billstein-Leber M, Carrillo CJD, Cassano AT, et al. ASHP Guidelines on Preventing Medication Errors in Hospitals. American Journal of Health-System Pharmacy. 2018;75(19):1493-517. https://doi.org/10.37573/9781585286560.179
6. Ertuna E, Arun MZ, Ay S, et al. Evaluation of pharmacist interventions and commonly used medications in the geriatric ward of a teaching hospital in Turkey: a retrospective study. CIA. 2019;14:587-600. https://doi.org/10.2147/cia.s201039
7. Rasool MF, Rehman A, Imran I, et al. Risk Factors Associated with Medication Errors Among Patients Suffering From Chronic Disorders. Front Public Health. 2020;8:531038. https://doi.org/10.3389/fpubh.2020.531038
8. Hodkinson A, Tyler N, Ashcroft DM, et al. Preventable medication harm across health care settings: a systematic review and meta-analysis. BMC Med. 2020;18(1):313. https://doi.org/10.1186/s12916-020-01774-9
9. Mutair AA, Alhumaid S, Shamsan A, et al. The Effective Strategies to Avoid Medication Errors and Improving Reporting Systems. Medicines. 2021;8(9):46. https://doi.org/10.3390/medicines8090046
10. Barber N, Taxis K. Incidence and severity of intravenous drug errors in a German hospital. European Journal of Clinical Pharmacology. 2004;59(11):815-817. https://doi.org/10.1007/s00228-003-0689-9
11. Ministry of Health. Continuity of patient safety training materials. 2014. Medical Publishing House, Hanoi.
12. Mulac A, Taxis K, Hagesaether E, et al. Severe and fatal medication errors in hospitals: findings from the Norwegian Incident Reporting System. Eur J Hosp Pharm. 2021;28(e1):e56-61. https://doi.org/10.1136/ejhpharm-2020-002298
13. Aronson JK. Medication errors: what they are, how they happen, and how to avoid them. QJM. 2009;102(8):513-521. https://doi.org/10.1093/qjmed/hcp052
14. Chua SS, Tea MH, Rahman MHA. An observational study of drug administration errors in a Malaysian hospital (study of drug administration errors). Journal of Clinical Pharmacy and Therapeutics. 2009;34(2):215-223. https://doi.org/10.1111/j.1365-
2710.2008.00997.x
15. Nguyen HT, Nguyen TD, van den Heuvel ER, et al. Medication Errors in Vietnamese Hospitals: Prevalence, Potential Outcome and Associated Factors. Emmert-Streib F, editor. PLoS ONE. 2015;10(9):e0138284. https://doi.org/10.1371/journal.pone.0138284
16. Tissot E, Cornette C, Limat S, et al. Observational study of potential risk factors of medication administration errors. Pharm World Sci. 2003;25(6):264-268. https://doi.org/10.1023/b:phar.0000006519.44483.a0
17. WHO. Mental health in Vietnam. 2022. Available from URL: https://www.who.int/vietnam/health-topics/mental-health
18. Höhn A, Oksuzyan A, Lindahl-Jacobsen R, et al. Gender differences in time to first hospital admission at age 60 in Denmark, 1995–2014. Eur J Ageing. 2021;18(4):443-451. https://doi.org/10.1007/s10433-021-00614-w
19. Dorothy A, Yadesa TM, Atukunda E. Prevalence of Medication Errors and the Associated Factors: A Prospective Observational Study Among Cancer Patients at Mbarara Regional Referral Hospital. CMAR. 2021;13:3739-3748. https://doi.org/10.2147/
cmar.s307001
20. Solanki N, Shah C. Root cause analysis of medication errors at a multi-specialty hospital in Western India. Int J Basic Clin Pharmacol. 2013;2(6):819. https://doi.org/10.5455/2319-2003.ijbcp20131228
21. Al-Worafi YM. Medication errors. In: Drug Safety in Developing Countries. Elsevier; 2020 [cited 2022 Dec 16]. p. 59–71. Available from: https://linkinghub.elsevier.com/retrieve/pii/B9780128198377000066
22. Shawahna R, Abbas A, Ghanem A. Medication transcription errors in hospitalized patient settings: a consensual study in the Palestinian nursing practice. BMC Health Serv Res. 2019;19(1):644. https://doi.org/10.1186/s12913-019-4485-3
23. Tariq RA, Vashisht R. Medication dispensing errors and prevention. 2018. Available from URL: https://www.ncbi.nlm.nih.gov/books/NBK519065/
24. Cavell GF, Mandaliya D. Magnitude of error: a review of wrong dose medication incidents reported to a UK hospital voluntary incident reporting system. Eur J Hosp Pharm. 2021;28(5):260-265. https://doi.org/10.1136/ejhpharm-2019-001987
25. Dirik HF, Samur M, Seren Intepeler S, et al. Nurses’ identification and reporting of medication errors. J Clin Nurs. 2019;28(5-6):931-938. https://doi.org/10.1111/jocn.14716
26. Hammod HJ, Mohammed DSJ. Effectiveness of an Educational Program on Nurses Knowledge Concerning Complications
Prevention of Mechanical Ventilation at Intensive Care Unit in Al- Hussain Teaching Hospital at Nassiryah City. 2016;6(2):149-159. https://doi.org/10.36321/kjns.vi20162.2658
27. Mostafa LS, Sabri NA, El-Anwar AM, et al. Evaluation of pharmacist-led educational interventions to reduce medication errors in emergency hospitals: a new insight into patient care. Journal of Public Health. 2019. https://doi.org/10.1093/pubmed/
28. Gebre M, Addisu N, Getahun A, et al. Medication Errors Among Hospitalized Adults in Medical Wards of Nekemte Specialized Hospital, West Ethiopia: A Prospective Observational Study. DHPS. 2021;13:221-228. https://doi.org/10.2147/dhps.s328824
29. Leili M, Nikvarz N. Evaluating the role of clinical pharmacist in the detection and reduction of medication errors in a specialized burn unit. 2022. Available from URL: https://pubmed.ncbi.nlm.nih.gov/35610074/.
30. Wheeler AJ, Scahill S, Hopcroft D, et al. Reducing medication errors at transitions of care is everyone’s business. Aust Prescr. 2018;41(3):73-77. https://doi.org/10.18773/austprescr.2018.021
31. De Oliveira GS, Castro-Alves LJ, Kendall MC, et al. Effectiveness of Pharmacist Intervention to Reduce Medication Errors and Health-Care Resources Utilization After Transitions of Care: A Meta-analysis of Randomized Controlled Trials. J Patient Saf.
2021;17(5):375-380. https://doi.org/10.1097/pts.0000000000000283
32. Jaam M, Naseralallah LM, Hussain TA, et al. Pharmacist-led educational interventions provided to healthcare providers to reduce medication errors: A systematic review and meta-analysis. Vaismoradi M, editor. PLoS ONE. 2021;16(6):e0253588.
https://doi.org/10.1371/journal.pone.0253588
33. Alzahrani AA, Alwhaibi MM, Asiri YA, et al. Description of pharmacists’ reported interventions to prevent prescribing errors among in hospital inpatients: a cross sectional retrospective study. BMC Health Serv Res. 2021;21(1):432. https://doi.
org/10.1186/s12913-021-06418-z
34. Nguyen KT, Le VTT, Nguyen TH, Pham ST, Nguyen PM, Taxis K, Vi MT, Nguyen T, Tran HD. Effect of Pharmacist-Led Interventions on Physicians’ Prescribing for Pediatric Outpatients. Healthcare (Basel). 2022;10(4):751. https://doi.org/10.3390/
healthcare10040751
35. Azrifitria A, Fauziyah S, Nur A. The Impact of Pharmacists’ Interventions to Prevent Medication Errors at a Tertiary Hospital in Central Jakarta, Indonesia. Pharm Biomed Sci J. 2019;1(1). https://doi.org/10.15408/pbsj.v1i1.12643
36. Karthikeyan M, Lalitha D. A prospective observational study of medication errors in general medicine department in a tertiary care hospital. Drug Metabolism and Drug Interactions. 2013;28(1). https://doi.org/10.1515/dmdi-2012-0032
fdy216
Article Sidebar
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.