Shedding light on pharmacists’ knowledge of kidney stones’ etiology and treatment

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Keywords

Pharmacists, Knowledge, Kidney Stones, Etiology, Treatment, Jordan

Abstract

Background: The recurring nature of kidney stones (KS) makes it difficult to control and treat. Patients’ education plays a part in reducing disease recurrence. Pharmacists participate in the healthcare services through educating patients with kidney stones about KS preventive measures and medications that greatly reduce the disease frequency and the treatment cost. Insufficient pharmacists’ knowledge may affect the services’ quality and result in misuse of KS medications. Objectives: To evaluate the pharmacists’ level of knowledge to provide adequate information about KS preventive measures, medications, and treatments for patients with kidney stones in Jordan. Methods: An online descriptive survey was distributed to pharmacists to assess their knowledge about KS causes, prevention, and treatment. The results were analyzed using the SPSS software. Results: There were 393 pharmacists participated in this study. Pharmacists demonstrated an overall intermediate level of knowledge about KS. They showed an excellent level of knowledge regarding KS types and etiology, an intermediate level of knowledge about KS preventive measures and treatment, and poor knowledge about home remedies and drugs that promote KS formation. Conclusion: Pharmacists knowledge about KS management through diet and medications need to be improved. This could be through focusing on pharmacists’ training for the effective implementation of knowledge in the clinical practice. Adopting guidelines by pharmacists may reduce the risk of KS recurrence and provide pharmacist-led patient education about KS management in hospitals and community pharmacies.

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References

1. JJEES_Vol9_N1_HQ_P4.pdf.2022. http://www.jjees.hu.edu.jo/files/Vol9N1/JJEES_Vol9_N1_HQ_P4.pdf
2. Scales CD, Smith AC, Hanley JM, et al. Prevalence of Kidney Stones in the United States. European Urology. 2012;62(1):160-165. https://doi.org/10.1016/j.eururo.2012.03.052
3. Parmar MS. Kidney stones. BMJ. 2004;328(7453):1420-1424. 2022. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC421787/4. Abboud I. Prevalence of Urolithiasis in Adults due to Environmental Influences: A Case Study from Northern and CentralJordan. 2018.
5. Rukin NJ, Siddiqui ZA, Chedgy ECP, et al. Trends in Upper Tract Stone Disease in England: Evidence from the Hospital Episodes Statistics Database. UIN. 2017;98(4):391-396. https://doi.org/10.1159/000449510
6. Nerli R, Jali M, Guntaka AK, et al. Type 2 diabetes mellitus and renal stones. Adv Biomed Res. 2015;4:180. https://doi.org/10.4103/2277-9175.164012
7. Borghi L, Meschi T, Guerra A, et al. Essential arterial hypertension and stone disease. Kidney International. 1999;55(6):2397-2406. https://doi.org/10.1046/j.1523-1755.1999.00483.x
8. Bargagli M, Ferraro PM, Vittori M, et al. Calcium and Vitamin D Supplementation and Their Association with Kidney Stone Disease: A Narrative Review. Nutrients. 2021;13(12):4363. https://doi.org/10.3390/nu13124363
9. Baatiah NY, Alhazmi RB, Albathi FA, et al. Urolithiasis: Prevalence, risk factors, and public awareness regarding dietary and lifestyle habits in Jeddah, Saudi Arabia in 2017. Urology Annals. 2020;12(1):57. https://doi.org/10.4103/UA.UA_13_19
10. Türk C, Petřík A, Sarica K, et al. EAU Guidelines on Diagnosis and Conservative Management of Urolithiasis. European Urology.2016;69(3):468-474. https://doi.org/10.1016/j.eururo.2015.07.040
11. Preminger GM, Tiselius HG, Assimos DG, et al. 2007 Guideline for the Management of Ureteral Calculi. Journal of Urology.2007;178(6):2418-2434. https://doi.org/10.1016/j.juro.2007.09.107
12. Rattu M, Shah N, Singhal S, et al. The role of pharmacists in the management of acute kidney stones. US Pharmacist.2013;38:HS4-HS8.
13. Frassetto L, Kohlstadt I. Treatment and prevention of kidney stones: an update. Am Fam Physician. 2011;84(11):1234-1242.
14. Portis AJ, Sundaram CP. Diagnosis and initial management of kidney stones. Am Fam Physician. 2001;63(7):1329-1338.
15. Heilberg IP, Goldfarb DS. Optimum Nutrition for Kidney Stone Disease. Advances in Chronic Kidney Disease. 2013;20(2):165-174. https://doi.org/10.1053/j.ackd.2012.12.001
16. Ferraro PM, Bargagli M, Trinchieri A, et al. Risk of Kidney Stones: Influence of Dietary Factors, Dietary Patterns, and Vegetarian–Vegan Diets. Nutrients. 2020;12(3):779. https://doi.org/10.3390/nu12030779
17. Pearle MS, Goldfarb DS, Assimos DG, et al. Medical Management of Kidney Stones: AUA Guideline. Journal of Urology.2014;192(2):316-324. https://doi.org/10.1016/j.juro.2014.05.006
18. Wallace RB, Wactawski-Wende J, O’Sullivan MJ, et al. Urinary tract stone occurrence in the Women’s Health Initiative (WHI) randomized clinical trial of calcium and vitamin D supplements. The American Journal of Clinical Nutrition. 2011;94(1):270-277. https://doi.org/10.3945/ajcn.110.003350
19. Gul Z, Monga M. Medical and Dietary Therapy for Kidney Stone Prevention. Korean J Urol. 2014;55(12):775-779. https://doi.org/10.4111/kju.2014.55.12.775
20. Nirumand MC, Hajialyani M, Rahimi R, et al. Dietary Plants for the Prevention and Management of Kidney Stones: Preclinical and Clinical Evidence and Molecular Mechanisms. International Journal of Molecular Sciences. 2018;19(3):765. https://doi.org/10.3390/ijms19030765
21. Prezioso D, Strazzullo P, Lotti T, et al. Dietary treatment of urinary risk factors for renal stone formation. A review of CLU Working Group. Archivio Italiano di Urologia e Andrologia. 2015;87(2):105-120. https://doi.org/10.4081/aiua.2015.2.105 
22. Alenzi M, Rahiman S, Tantry BA. Antiurolithic effect of olive oil in a mouse model of ethylene glycol-induced urolithiasis. Investig Clin Urol. 2017;58(3):210-216. https://doi.org/10.4111/icu.2017.58.3.210
23. Nirumand MC, Hajialyani M, Rahimi R, et al. Dietary Plants for the Prevention and Management of Kidney Stones: Preclinical and Clinical Evidence and Molecular Mechanisms. International Journal of Molecular Sciences. 2018;19(3):765. https://doi.org/10.3390/ijms19030765
24. Joshi A, Tallman JE, Calvert JK, et al. Complementary and Alternative Medicine Use in First-time and Recurrent Kidney Stone Formers. Urology. 2021;156:58-64. https://doi.org/10.1016/j.urology.2021.05.084
25. Stiani SN, Syahidah FM, Fikriani H, et al. Anticalculi activity of apigenin and celery (Apium graveolens L.) extract in rats induced by ethylene glycol–ammonium chloride. Journal of Pharmacy and Bioallied Sciences. 2019;11(8):556. https://doi.org/10.4103/jpbs.JPBS_202_19
26. PharmacistsImpactonPatientSafety_Web.pdf. Accessed June 5, 2022. https://pharmacist.com/Portals/0/PDFS/Practice/PharmacistsImpactonPatientSafety_Web.pdf?ver=dYeAzwlN3-PG9eSkMMsV-A%3D%3D
27. Tsuyuki RT, Beahm NP, Okada H, et al. Pharmacists as accessible primary health care providers: Review of the evidence. CanPha rm J (Ott). 2018;151(1):4-5. https://doi.org/10.1177/1715163517745517
28. Hayhoe B, Cespedes JA, Foley K, et al. Impact of integrating pharmacists into primary care teams on health systems indicators: a systematic review. Br J Gen Pract. 2019;69(687):e665-e674. https://doi.org/10.3399/bjgp19X705461
29. AbuRuz SM, Alrashdan Y, Jarab A, et al. Evaluation of the impact of pharmaceutical care service on hospitalized patients with chronic kidney disease in Jordan. Int J Clin Pharm. 2013;35(5):780-789. https://doi.org/10.1007/s11096-013-9806-8
30. Murugan H, Spigner C, McKinney CM, et al. Primary care provider approaches to preventive health delivery: a qualitative study. Prim Health Care Res Dev. 2018;19(5):464-474. https://doi.org/10.1017/S1463423617000858
31. Saqib A, Atif M, Ikram R, et al. Factors affecting patients’ knowledge about dispensed medicines: A Qualitative study of healthcare professionals and patients in Pakistan. PLOS ONE. 2018;13(6):e0197482. https://doi.org/10.1371/journal.pone.0197482
32. Bruchet N, Loewen P, de Lemos J. Improving the Quality of Clinical Pharmacy Services: A Process to Identify and Capture High- Value “Quality Actions.” Can J Hosp Pharm. 2011;64(1):42-47.
33. Kadhum H. Assessment of Patient’s Knowledge about Avoidance of Recurrent Urolithiasis . 2018. https://www.researchgate.net/publication/326976916_Assessment_of_Patient’s_Knowledge_about_Avoidance_of_Recurrent_Urolithiasis_albwlyt_almsalk_hsy_tkrar_mn_hwl_almrdy_marf_tqyym
34. Yusof A, Chia YC, Hasni YM. Awareness and Prevalence of Mammography Screening and its Predictors - A Cross Sectional Study in a Primary Care Clinic in Malaysia. Asian Pacific Journal of Cancer Prevention. 2014;15(19):8095-8099. https://doi.org/10.7314/APJCP.2014.15.19.8095
35. Sperber A, DeVellis R, Boehlecke B. Cross-Cultural Translation. Journal of Cross-Cultural Psychology. 1994;25:501. https://doi.org/10.1177/0022022194254006
36. Elm E von, Altman DG, Egger M, et al. Strengthening the reporting of observational studies in epidemiology (STROBE) statement:guidelines for reporting observational studies. BMJ. 2007;335(7624):806-808. https://doi.org/10.1136/bmj.39335.541782.AD
37. Sample Size Calculator by Raosoft, Inc. Accessed June 24, 2020. http://www.raosoft.com/samplesize.html
38. Bos D, Abara E, Parmar MS. Knowledge, attitudes, and practice patterns among healthcare providers in the prevention of recurrent kidney stones in Northern Ontario. Canadian Urological Association Journal. 2014;8(11-12):e795-804. https://doi.org/10.5489/cuaj.1455
39. Tarplin S, Monga M, Stern KL, et al. Predictors of Reporting Success with Increased Fluid Intake Among Kidney Stone Patients.Urology. 2016;88:49-56. https://doi.org/10.1016/j.urology.2015.10.024
40. Scales CD, Desai AC, Harper JD, et al. Prevention of Urinary Stones with Hydration (PUSH): Design and Rationale of a Clinical Trial. American Journal of Kidney Diseases. 2021;77(6):898-906.e1. https://doi.org/10.1053/j.ajkd.2020.09.016
41. Borghi L, Meschi T, Amato F, et al. Urinary Volume, Water and Recurrences in Idiopathic Calcium Nephrolithiasis: A 5-year Randomized Prospective Study. Journal of Urology. 1996;155(3):839-843. https://doi.org/10.1016/S0022-5347(01)66321-3
42. Krieger NS, Bushinsky DA. The Relation Between Bone and Stone Formation. Calcif Tissue Int. 2013;93(4):374-381. https://doi.org/10.1007/s00223-012-9686-2
43. Betz M. Whole Diet Approach to Calcium Oxalate Kidney Stone Prevention. Journal of Renal Nutrition. 2022;32(1):e11-e17.https://doi.org/10.1053/j.jrn.2021.10.00544. Siener R. Nutrition and Kidney Stone Disease. Nutrients. 2021;13(6):1917. ttps://doi.org/10.3390/nu13061917
45. Taylor AM, Bingham J, Schussel K, et al. Integrating Innovative Telehealth Solutions into an Interprofessional Team-Delivered Chronic Care Management Pilot Program. JMCP. 2018;24(8):813-818. https://doi.org/10.18553/jmcp.2018.24.8.813
46. Jarab AS, Al-Qerem W, Mukattash TL, et al. Pharmacy and Pharm.D students’ knowledge and information needs about COVID-19. International Journal of Clinical Practice. 2021;75(3):e13696. https://doi.org/10.1111/ijcp.13696
47. Ng JY, Tahir U, Dhaliwal S. Barriers, knowledge, and training related to pharmacists’ counselling on dietary and herbal supplements: a systematic review of qualitative studies. BMC Health Serv Res. 2021;21(1):499. https://doi.org/10.1186/s12913-021-06502-4
48. Abdel Qader DH, Silverthorne J, Al-Jomaa EE, et al. Jordanian pharmacists’ knowledge of issues related to using psychotropic medications a cross-sectional study. IJPR. 2021;13(3). https://doi.org/10.31838/ijpr/2021.13.03.045
49. Zawiah M, Yousef AM, Khan AH, et al. Food-drug interactions: Knowledge among pharmacists in Jordan. PLoS One. 2020;15(6):e0234779. https://doi.org/10.1371/journal.pone.0234779